SynCell-nExUs Supervisors

Charlotte Aumeier

University of Geneva, Biochemistry Department, Switzerland

Charlotte Aumeier is an associate Professor of Biochemistry at the University of Geneva, Switzerland. After earning her PhD at the University of Bonn on the cytoskeleton of diatoms and completing postdoctoral work at the University of Grenoble, France, she established her laboratory in Geneva in 2018. Her research combines protein purification, semi-synthetic protein design, in vitro reconstitution assays, and quantitative cell biology to study microtubule dynamics, network organisation, and motor–microtubule interactions. By integrating mechanistic in vitro reconstitution with in vivo validation, her group uncovers the molecular principles governing cytoskeletal organisation and function, also in non-standard model organisms.

”Cells have a complex actin and microtubule cytoskeleton network. This network is essential for many processes in cells: cell migration, division, differentiation.
We want to understand how the cytoskeleton is organized and regulated in space and time, resulting in a functional architecture. To understand the underlying principles, we study the cytoskeleton dynamics, mechanics and interactions using divers systems: reconstitution systems using cytoskeletal protein including microtubules, motors and phase separating proteins, and verify their role in living cells including immune and muscle cells, and diatoms.”

For more information, visit the Charlotte Aumeier Lab website.

Main area(s)Sub-area(s)
Synthetic cell division and replicationMinimal contractile cytoskeletons and division rings
Condensate-based minimal cell division
Artificial motility systems
Synthetic mitotic spindle assembly