Cees Dekker
Delft University of Technology, Netherlands
Cees Dekker is a Distinguished University Professor at TU Delft. Being trained as a physicist, he developed many single-molecule nanotechnologies that he applies to a variety of biological questions – yielding many discoveries, from SMC molecular motors to nanopore sequencing. He published over 400 papers that got cited nearly 100,000 times (H-index 136). Next to his own research, he leads the Dutch national EVOLF consortium (46 M€, 31 PIs) that aims to build a synthetic cell.
“Our lab does leading single-molecule biophysics research on chromosome motors, nanopore protein sequencing, and synthetic cells. Our synthetic cell research focuses on building a synthetic divisome (using archaeal CDV proteins, bacterial DynaminA, and/or RNA origami structures), DNA segregation (studying entropic DNA segregation in confinement), as well as synthetic genomes (designing/assembling 100+ kbp genomes, studying promotors and transcription). The group aims at research at the highest international level. Outstanding experimentalists that fit into this environment are invited to apply.”
For more information, visit the Cees Dekker Lab website
Photo by Merlijn Doomernik (All rights reserved)
| Main area(s) | Sub-area(s) |
|---|---|
| Synthetic cell division and replication | Minimal contractile cytoskeletons and division rings Minimal chromosome segregation DNA partitioning in artificial cells Artificial nucleoid occlusion systems |
| Information processing and evolution of synthetic cells | Minimal chromosome/chromatin/nucleoid Artificial nucleus Chromosome segregation model |
| Enabling technologies for synthetic cells | DNA origami-based modules for synthetic cells RNA origami-based modules for synthetic cells Droplet-based microfluidics Phospholipid-based Synthetic Cells |